In-N-Out Burger is known for offering relatively affordable prices compared with many other fast-food restaurants. Its menu focuses on burgers, fries, and milkshakes, allowing customers to enjoy a filling meal without spending too much. Prices vary depending on the restaurant's location, local taxes, and menu changes. Single burgers generally cost less than double or triple-patty options, while combo meals can cost more because they include fries and a drink. The restaurant also offers customizations, such as Animal Style, that make it possible to change your order without choosing from a large, expensive menu.

For example, a typical burger may cost around $3–$4, a cheeseburger around $4, and a Double-Double around $5.50–$6.50. Fries generally cost about $2–$3, and milkshakes about $3–$4, although actual prices vary by location. A full meal with a burger, fries, and a drink may cost roughly $8–$12 before tax. It is very good value for the quaitlaly.